Exotoxin |
Endotoxin |
|---|
| Produced by both Gram-positive and Gram-negative bacteria | Produced only by Gram-negative bacteria |
| Released from cell | Integral part of cell wall |
| Protein | Lipid A of lipopolysaccharide |
| Many types of exotoxin based on structure and function |
Only one type of endotoxin |
| Heat labile | Heat stable |
| Specific receptors on host target cells |
Diverse range of host cells and systems affected |
| Specific effects in host | Diverse range of effects in host |
| Toxoids can be made by treating with formalin |
Toxoids cannot be made |
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